Nick Reiner was diagnosed with schizophrenia and his medication was adjusted before his parents’ murders, sources say.

LOS ANGELES — Nick Reiner had been diagnosed with schizophrenia and his medication was changed or adjusted at some point before the murders, according to three sources with direct knowledge of the case.

A sealed medical order was signed Friday by the judge overseeing the initial stages of the 32-year-old’s case, where he is charged with two counts of murder in the deaths of his parents, the acclaimed filmmaker. Rob Reiner, 78, and Michele Singer Reiner, 70.

This sealed order may relate to Reiner’s mental health condition and treatment. The sources declined to discuss the content of the order.

Reiner was being treated for a severe psychiatric disorder at the time of his parents’ murder, the three sources said.

He was diagnosed with schizophrenia several years ago and was treated with medication, the sources said. It is not clear when his medication was changed.

As of Friday, the weapon used in the killings had not been found, two of the sources said. However, they said it was of limited investigative value given all the other evidence in the case, which includes what was found at the crime scene, items recovered during the arrest and Reiner’s alleged statements to police.

The Reiners were found dead in the bedroom of their home in Brentwood, on the west side of Los Angeles, the city’s Assistant Police Chief Dominic Choi said Tuesday. The couple was stabbed to death “in the early morning hours” on Sunday, the Los Angeles County District Attorney’s Office said.

Their cause of death was ruled multiple blunt force injuries, and the manner homicide, the Los Angeles County Medical Examiner’s Office ruled.

Nick Reiner was arrested shortly after 9:00 p.m. Sunday night in University Park, near the University of Southern California, about 15 miles from his parents’ home.

He was being held without bail at the Twin Towers Correctional Facility in downtown Los Angeles, according to inmate records.

it appeared in a court in Los Angeles on Wednesday wearing a blue vest. His trial has been postponed twice, and his next appearance is set for January 7. His lawyer, Alan Jackson, previously said his trial was initially postponed because he was not medically cleared in time for the hearing.

Two of the Reiners’ children, Jake and Romy Reiner, released a statement Wednesday about the “horrific and devastating” deaths of their parents, whom they also called their best friends.

“We now ask for respect and privacy, for speculation to be tempered with compassion and humanity, and for our parents to be remembered for the incredible lives they lived and the love they gave,” they said in a statement.

Andrew Blankstein, Eric Leonard and Dennis Broad reported from Los Angeles and Marlene Lenthang from Chicago.